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Physiology p2


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1) Reproductive system 

1 Sperms produce an enzymatic substance for dissolving egg covering is called as @hyaluonidaase

2 Ovulation or release of ovum occurs on which day of menstrual cycle @12_14days

3 Menstruation result in discharge of@endometrial lining

4 Which one of the following is the precise site of embryonic implantation in a normal pregnancy @endometrium

5 Follicular atresia is@degeneration of follicles

6 Which of the following group of cells in male gonad represent haploid cells@2nd ary spermatocytes

7 Shortest phase in menstruation cycle of women is @ovulatory phase 

8 Which gland releases of small amount of liquid just prior to ejaculation to decrease acidity in urethra caused by urine@bulbourethral gland

9 Head of mature sperms is made up of @Acrosome

10 Hormones secretedbby human placenta@Human chorionic gonadotropin hormone, oestrogen & progesterone, relaxin

11 Menopausal hot flushes is due to decreased estrogen

 12 The cells of interestitial compartment of the testis@are unable to function unless the testis descends into scrotum

13 The harmone testosterone is secreted by@intestinal cells

 14 The acrosome of the sperm contains @nucleus

15 The cytoplasmic part of sperm cell is the @body

16 Testosterone causes@sperm to be motile

17 Human spermatozoa@contain 23 chromosomes

18 Synthesis of the testosterone is by @interstitial cell

19 spermatogenesis is facilitated by @testosterone

20 Flagellum is which structure of the sperm @tail

21 The speed velocity of sperm is about @1_4mm/min

22 Acrosome of the sperm has enzymes@proteolytic enzyme

 23 The condition of failure of a testis to descend from abdomen to scrotum is called as@cryptorchism

 24 Spermatogenesis is the maturation of @sperm

25 ---------- maintains the pregnancy @Corpus luteum

26 A specialised inner mucous membrane of the uterus is @endometrium

27 Nutrition & Respiration to the embryo is maintained by @placenta

28 Maturation and development of the ovarian follicles is regulated by@FSH

 29 Ovulation occurs under the influence of @LH

30 Characteristic histological variation in females life is occurs only in @ovary

31 Cyclical discharge of blood from the uterus in females reproductive life is called as@mentruation

 32 The process of rupture of graffian follicle isaovulation

 33 Ovulation occurs usually between---------after the 1 st day of menstruation@13_17th week

 34 The mechanism that determines the location of the blastocyst is called as @implantation

35 -------days after ovulation an implantation occurs@7&9th

 36 Estrogen & progesterone are ---------- hormones.@ovarian

 37 Gonadotropins FSH & LH are secreted by @anterior pituitary

38 The active principal of corpus luteum is@progesterone

39 Permanant cessation of menstruation is called as----@menopause

40 All the nutritivents from the maternal blood passes into the foetus through @placenta

41 At the beginning of lactation the secretion of mammary gland is called as @colostrum

42 The process of maintenance of lactation is controlled by@prolactin

 43 ------ is for the milk let down reflex.@oxyticin

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2) Nervous system

1 The synoptic vesicle in a neuro muscular junction discharges@acetylcholine

 *2 In the left cerebral hemisphere buoca's area is related to@speech

3 Which of the following structure at a synopse has neurotransmittors@synaptic vesicle

 4 Brain stem does include@pons vardii,medulla oblangata, midbrain

5 Node of Ranvier occurs where@myelin sheath is discontinous

*6 Which of the following parts of brain is called emotional brain@limbic system

 7 The sensory neuron enters the spinal cord through@the dorsal root of the spinal cord

8 Emmediately after an action potential has peaked which cellular gates open@potassium

 *9 Sensory tracts in posterior columns are@tarct of gall

10 Unipolar neurons are found only in@early embryo

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3) Endocrine system

1 Hypothalamic releasing factors which control the secretory function of the anterior pituitary reach the anterior pituitary via@hypothalamo_hypophysial portal system

2 Atrophy of the anterior pituitary in infants and childrens produces @dwarfism

3Which of the following has both activating and inhibiting effects on ACTH secretion@cerebral cortex

 4 The thyroid gland contains about@20%of total iodine content of body

5 Secretion of parathormone is controlled by @blood calcium level

6 Glycogen secretion is inhibited by@hyperglycaemia

7 Oxytocin shares some of the activities of ADH and thus it is@minimally diuretic

8 Glycogen is secreted by alpha cells of islets of langerhans@it is polypeptide in nature

 9 In extreme cases of diabetes insipidus maximum output of urine may be high as@28_30litre

10 vasopressin is synthesised in @hypothalamic nuclei

11 Ejection of milk from breast or let down@it caused by Oxytocin induced contraction of the myoepithelial thesis

12 The earliest effect occurs following the administration of TSH is@increase thyroxin synthesis

13 The following test asses the thyroid function @BMR,iodine uptake studies, protein bound iodine

14 Therapy of thyroxin in hypothyroid patients improves the following @gastrointestinal motility

 15 Which of the following would decreases in hyptothyroid patients@food intake

 16 During primary active transport @substance is moved to higher concentration

17 Viterious humor lies@ behind lens 

*18 Ear ossicles are arranged in following order from ear drum @incus,malleus, stapes

19 The type of taste that is most sensitive to minute concentrations of the substance to be tasted is @the sweet taste

20 Sinus rhythm is produced due to@S.A.node

 21 The action of parathormone on kidney tends to@eleventh serum phosphate

22 The major site of action of insulin are@muscledliver

 23 Which of this is not hormone@maltose

 24 Life saving harmone are secreted by @pituitary

25 True about antidiuretic harmone is@secreation determine by Plasma osmolality, increase permeability of distal nephrons to water, secreated by nerve cells with their cell bodies in hypothalamus 

26.

27 

 28 Destruction of anterior lobeof pitutary gland (Simmond's disease) is characterized @infertility,asthenia, decrease BMR

 29 What is true about oxytocin@important to maintaining preganancy

30 Melanocyte stimulating hormone is secreted by @intermediate lobe of Pituitary gland

31 A hormone synthesised in the hypothalamus is @vasopressin

32 Posterior pituitary gland secretes@lxytocin & ADH

33 Diabetes insipedus is caused by deficient secretion of@vasopressin

 34 Secretion of growth hormone is inhibited by@somatostatin

 35 Secretion of prolactin is regulated by@prolactin release inhibiting hormone

36 Hormone secreted by ovary @estrogen

37 Toxic goitre caused due to@excessive secretion of thyroid hormone

38 Function of thyroid hormone@carbohydate metabolism, increase BMR, increase O2 consuption

39 secretion of thyroid hormone is regulated by@hypothalamus, Ant. Pituitary, feed lack regulation

40 Thyrotoxicosis is associated with@tachycardia

 41 Calcitonin is synthesised in@thyroid gland

42 Glycosuria is condition @excess blood vlolucose level

43 Hyoglycemia meaning @low blood glucose level

44 Carpus leutium is@remenant of grafian follicle, yellow colored body, gland which secret progesteron

45 Insulin secreted by@B_cell

 46 Features of tetany @carpopedal spasm, laryngeal striador, Erbs sigmln

47 Growth hormone secreted by @acidophilic cell

48 ant Pituitary gland secrete hormone@GH,TSH,ACTH,LH,FSH,Protactin 

49 Post Pituitary gland secrete hormone@ADH(vasopressin)

 50 Action of antidiuretic hormone@retention of water

51 Giangatism is disorder of@ant.pituitary

 52 Dwarfism@stunted growth, deficiency of growth hormone, regard skeletal growth

53 function of gonadotrofins @stimulation of spermatogenesis, Ovulation, development of grafian follicle

54 Cushing syndrome cause by Obesity, hypersecreation of cortisol(glucocorticoid) 

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4) Nerve Muscle Physiology

1 Skeletal and cardiac muscle,which are both striated at resting length contain an A band in each sarcomere.This A band contains@ all myosin +some actine

2 When skeleton muscle shortens in response to stimulation there is@A decrease in the width of I Band

3 A cross section view of skeletal muscule fiber through the H zone would reveal the presence of @myosin but no actin

4 Which of the following binds Ca++ in order to uncover the active site on F-action @troponin

5 The action potential of skeletal muscle@spread inward to all parts of muscle via T_tubules

6 Depolarization of T tubule is directly linked to thw opening of Ca+ channels on the sarcoplasmic reticulum of@skeletal muscle

 7 Which of the following is true about the synoptic channels on the endplate of skeletal muscle?@they are activated by (ACH) acetylcholine

*8 Which of the following about smooth muscle contraction is most accurate@does not require an action potential

 *9 Which of the following is only associated with skeletal muscle@troponin

10 Smooth muscle contraction is terminated by which of the following@dephophorylation of myosin light chain

11 The important ions involved in the nerve conduction are @K&Ca

12 Denervation of skeletel muscles leads to @atrophy,splastic paralysis, fibrulation

13 Surfactant _________@reduce surface tension with alveoli, Chemically as spinomylin

14 "Keratin" synthesised in@langerbans cells

 15 Carotene in the cutis vera is@yellow orange pigment of skin

5) Digestive system

1 Which of the following digestive juices has the minimum pH value@gastric juice

 2 In adults,curdling of the milk in small intestine occurs due to the action of @chymotrypsin

3 Duodenum has characteristic buunner's gland which screte two hormones called@secretin,cholecystokinin

4 Which of the following is correct@parietal cell secret hydrochloric acid

5 Least peristalsis occurs in@rectum

 6 Essentially the word digestiob means @hydrolysis of food

7 Digestion of carbohydrates is affected by@amylase

 8 Mucin in saliva is made up of @phopholipid

 9 Protein digestion is carried out by@proteolyolytic enzymes, proteoses, peptides

10 The structure which prevents entry of blood into respiratory tract is@epiglottis

 11 Succus entericus is secreated by@crypts of leiberkunn & Brunner gland

12 The principal function of gastro-oesophageal sphincter isato prevent reflux of stomach content

13 Digestion is chemically@hydrolysis

 14 Pancreatic secretion contains @tripsin

15 Brunner's glands secrets @mucus

16 Digestive enzyme secretes by salivary glands@ptyline

6) Vitamins 

1 Good Sources of Vitamin A and Vitamin D is @cod liver oil

 2 Vitamin A deficiency is responsible for @night blindness

3 Vitamin which is destroyed on heating is@vit.C

 4 What does a person suffering from bleeding gum need in his food@citrus fruits

Also read :ABDOMEN & PELVIS

 5 Vit. E prevents rancidity by virtue of its property @antioxidant

6 Iodine is essential for formation of @thyoxin

7 Anti sterelity vitamin is @vit.E

8 Ascorbic acidity deficiency causes @scurvy

9 Which vitamin deficiency causes Beriberi@thiamine

10 Which vitamin is called 'Antisterlity' vitamin @vit.E

11 Niacin deficiency causes@pellagra

 12 Which of the following  found in Pellegra@drlermatitis,diarrhea,dementia

 13 Nyctalopia is the deficiency of @vit.A

14 Vitamin A stored in the body as @retinol Ester 

15 Vitamin K is called as @antihaemorrhagic

16 Which of the following not water soluble vitamin @calciferol

17 Which of following acts as coenzyme for carboxylase@biotin. 

18 Which is not Vitamin C deficiency sign@haemorrhage,delay blood clotting, delay healing

19 Deficient production of insulin takes place in vit.deficiency@vit.c

 20 Exposure of sunlight decreased the requirement of @vit.D

21 Vitamin A stored in the body in @liver

22 Nyctalpia means @inability to see in dim light. 

23 Cholecalciferol is formed in @skin

24 Skeletal deformities found in @rickets

25 Vitamin B12 absorbed in @ileum

26 Following which constituent present in normal diet@Protein,carbohydrates,fats

 27 Energy yielding nutrients are@Protein,carbohydrates,fats

28 proyein deficiency disease known as@kwashiokor

29 followling which type of protein present in milk@caseinogen, lactalbu., lactglobulin

30 What is the ratio of protein fat & carbohydrate in diet @1:1:4

31 For vegeterians pulces are important source of@ carbohydate

32 kwashiorkor occurs when th diet is severly deficient@protein

 33 Marasmus occurs in deficiency of@protein

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7) Special Senses

1 Visual cortex for vision located@on medial surface of Occipital lobe

2 What happens to light rays when confrontong a convex lens@converge

3 Refratory index of crystline lens is @1.4

4 Visual acuity is tested with test chart palced at@20feet

 5 Fuction of stapedius is@protection of cochlea from loud sound, make low frequency sound, decreased sensitivity to own speech

6 Foot plate of stpes covers @oval window

7 Which of the following is not primary taste sensation @pungent

8 The taste buds are present on which type of papillae@circumvallete, fungi form,  foliate, 

9 The odour is sense by@mitral cell, tufted cell, glomerulus

10 The rod in the retina@are rendered by_insensitive by bright light

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8- Gastro-intestinal system 

1 Which of the following sentence regarding taste buds are @Test buds possessesmelon shaped and frequent supporting or sustentacular, The taste cell varies from 4 to 20% taste buds, Taste cells are responsible for detection of taste

2 Foliate papillae are found on ----@on lateral margin of the Posterior part of the tongue

3 The secretion of parotid gland carried out by a single duct called--@duct of stensen

4 Which of the following statement regarding salivary gland cells is true?@on lateral margin of the post. Part of the tongue

5 The secretion of serous gland is---@thin watery poor in solid but rich I enzymes.i.e.Ptyalin--

6 The following of type cells in the fundus and body part of stomach--@Mucus neck cells secret mucus which is swollable & contain mucinogen dopiest,,Chief cells or zymogenic cells secretspepsin and contain zymogein granules which are precussor of pepsin

7 The hormones secreted by stomach is-@gastrin

--8 Which of the following statement is true@In jejunum mucosa is throwninto the circular fold called as folds of kerckring,, --In jejunum numberof villi is less which help for the secretion,,The brush borderof the surface epithelial cells of villi is composed of microvilli --

9 Brunner’s gland is present-@duodenum

10 The Enzyme present in saliva@kallikrein which acts on Plasma protein to produce kallidin or brydykinin

--11 The composition of gastric juice is as follows-@water_98.45%, solid_1.5%

-12 The total quantity of pancreatic juice is@1500ml/day

 -13 Intestinal juice enzymes are--@erepsin and arginase are proteolytic enzyme ,amylase Sucrase, Maltase are carbohydrates splitting enzymes, Alkaline phosphatase cholestrolestrase are also the enzymes

  14 Which of the following statement is false regarding bile -----?@Solids contains are more in gall bladder bile, Bile salts are more in gall bladder bile. Mucin & pigments are less in liver bile 

15 Bile is essential for complete digestion of fats for and for fat absorption@ Due to the hydrotropic action and reducing the surface tension of the absorbing epithelium, increase theirpermeability and facilitate absorption

 --16 The different bile salts are -@sodium taurochoclate and sodium glychoclate

 ---17 Whichof the following sentences are true ---@The salivary center consists of superior and inferior nuclei in the reticular formation of medulla 

-18 The characteristic of appetite juice are --@The composition is constant does not vary with the type of food, acidic in reaction, rich in pepsin

-19 Hormones influence gastric secretions are ------@Glucocortecoids secreted by adrenal cortex increases acid and pepsin secretion -

20 The main excretory duct of pancreatic gland is ---@duct of wirsung

-21 Which of the following sentence is true@Pancreatic secretion is a reflex response,The vagus stimulation increase the pancreatic stimulation, The stimulation of symphatic nerve may decrease secretion of pancreatic juice 

22 Which of the following is stimulation for pancreatic secretion?@pancreozymin,heptocrinin

 23 The total amount of bile secretion—@800_1000ml/day

 24 Which of the following sentence is true?@Chemical substances pass via the body fluids & act on the chemo sensitive area called chemoreceptorstrigger zone in the floor of IV ventricle & cause vomiting 

25 Peristalsis is a -----@composite wave, it consist of wave of contraction followed by wave of relaxation, it travel down the gut in a aboral direction

26 The movement of villi stimulated by hormone@villikinin

 27 Following are the movements of large intestine @segmental contraction, haustal contraction, kneading movement

No peristalsis shown by large intestine(Divya Notes) 

– 28 Pecularities of action of pancreatic amylase are as follows @it acts both on boiled & unboil starch

29 Invertase actson sucrose producing @1mol.of fructose & 1mol.of glucose

30 Characteristics of trypsin is—@protein in nature

31 Function of bite salts include @emulsification of fats

32 Icterus is seen when serum billrubin is above @2mg%

33 Main functions of large intestine is@absorption of water & electolytes

34 Which of the following has  rule of liver?@glycogen storage, synthesis of coagulation factor, absorption of iron

35 Gastrin sectretion is inhibited by aexcess HCL

36 Which of the following is  a function of bile juice@emulsification of fats, absorption of cholesterol, miscells formation 

*37 In GIT smooth muscle, the depolarization is due to opening up of@ca++ channel

 38 Intrinsic factor is secreted by which cells?@parietal

 39 HCl secretion is  stimulated by @fasting,emotional stress, somatostatin

40 Vitamin B12 is produced by@bacteria in colon

41 Gastrointestinal movements, controlled by@auerbach's plexus

 42 Cells of stomach which play major role in digestion of protiens @chief cell

43 All of the following are clinical features of myxodems @dry scaly skin, decrease BMR, decrease pulse rate

44 Following hormone is an example of of neuroendocrine secretion@growth hormone

 45 Delta cells of Panceras secrete @somatostatin

46 Which of the following controls the secretion of prolactin? @somatomammotrophin

47 Mechanism of action of ADH is to@make ascending limb of henle permeable to water

48 A 40 year old female patient came with a complaint of change in voice,swelling of face and intolerance to cold.She is most likely to have@hypothyroidism

49 Mental retardation with dwarfism occurs due decreased secretion of@growth hormone

 50 Following are true insulin @glycopeptide, secreat by B_cell

51 Excess of growth hormone secretion in adults leads to@ Acromegaly

52 Ovulation is promarily caused by preovulatory surge of@leutinizing hormone(LH surge-14th day of MC) 

53 A 60 year old male patient came with complaints of increase appetite,increase frequency of urination and increase thirst. He is most likely to have@diebetes insipidus

54 Which one of the following factors causes increase in GFR?@increasse in glomerular capillary hydrostatic pressure, increase in colloidal osmotic pressure of plasma, increase on capsular pressure

55 ADH increases permeability of collection duct to @water

56 GFR is _____litres per day@180L

 57 The substance for Renal clearance test which develops the renal plasma flow is@PAH

 58 GFR is increased when@Renal blood flow is increased 


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